从“邪伏肺络、因瘀致虚”析特发性肺纤维化

Analysis of Idiopathic Pulmonary Fibrosis with Theory of “Pathogen Hiding in Lung Collaterals and Blood Stasis Causing Lung Weakness”

特发性肺纤维化完整的发病机制尚不明确,基于已知认识,从中医理解为"邪伏肺络是病因,枢机不利启动血瘀、瘀血内结致新血不生是过程,肺、脾、肾气虚是结果,气血失和可加速疾病进展,引动伏邪易诱发急性加重"。脏非本虚,是"因瘀致虚、互为因果",且"瘀"含两端,即气郁、血瘀,故瘀解则虚复,治疗攻瘀忌猛,重在枢转气机、养血活血、疏通肺络。

The pathogenesis of idopathic pulmonary fibrosis（ IPF） is not well recognized in recent days.Based on what has already been known,the physiopathology of IPF could be interpreted under the perspective of TCM,which is that＂the hidden pathogen in lung collaterals triggers the disease and then the dysfunction of cardinal system results in the blood stasis,which blocks the generation of new blood.Qi deficiency of lung,spleen and kidney is the result.Unbalance of qi and blood as well as provoking of the hidden pathogen will aggravate the disease.＂The lung is inherently weak,and＂the weakness and stasis result in each other＂.Stasis consists qi depression and blood stasis.Therefore,once stasis is solved,the weakness will recover.It is not advised to treat stasis aggressively,it is significant to promote qi movement,nourish and activate blood and dredge lung collateral channels.