黄芪建中汤加减治疗脾胃气虚证功能性消化不良临床研究

Clinical Curative Effect of Huangqi Jianzhong Decoction in the Treatmen of Functional Dyspepsia with Insufficiency of Spleen-qi and Stomach-qi Syndrome

目的:研究黄芪建中汤加减治疗脾胃气虚为主症功能性消化不良的临床疗效。方法:将临床诊断脾胃气虚证或为主症型的功能性消化不良患者221例随机分为观察组(120例)和对照组(101例),对2组Hp感染者均加用四联抗Hp治疗10 d,观察组同时应用黄芪建中汤加减治疗,对照组应用吗丁啉治疗,2组均以14 d为1个疗程,连服2个疗程,随访观察4周,观察2组患者治疗前后主要临床症状、舌质、舌苔、脉象等指标的变化。结果:黄芪建中汤治疗脾胃气虚为主症功能性消化不良疗效与对照组比较差异有统计学意义(P<0.05)。结论:黄芪建中汤加减治疗脾胃气虚为主症的功能性消化不良具有治愈率高、疗效显著等特点,值得临床推广辨证应用。

Objective： To observe the clinical curative efficacy of Huangqi Jianzhong decoction in the treatment of functional dyspepsia with insufficiency of spleen-qi and stomach-qi syndrome. Methods： A total of 221 cases of the spleen-qi and stomach qi insufficiency syndrome or the main syndrome of functional dyspepsia were randomly divided into observation group（120 cases） and control group（101 cases）. Two groups of patients with Hp infection were treated with quadruple anti-Hp therapy for 10 days. The control group used domperidone,and the treatment group used Huang qi Jianzhong decoction on the basis of domperidone. Fourteen days for 1 course,and both groups were treated by 2 courses and followed up for 4 weeks. To observe the changes of indexes of tongue nature,furred tongue,pulse condition,and so on in two groups before and after treatment. Results： The difference of efficacy between the observation group and the control group was statistically significant（P〈0. 05）. Conclusion： Treating Functional dyspepsia with insufficiency of spleen-qi and stomach-qi syndrome by Huangqi Jianzhong decoction can achieve high efficacy,and it is worthy to be used in clinical application.