穴位艾灸治疗肿瘤化疗所致白细胞减少临床观察

Clinical Observation of Acupoint Moxibustion on Leukocytopenia Caused by Tumor Chemotherapy

目的:探讨穴位艾灸治疗肿瘤化疗所致白细胞减少的临床疗效。方法:选择深圳市第二人民医院2013年1月至2015年6月收治的肿瘤化疗后白细胞减少患者82例,按照随机数字表法分为2组,每组41例,对照组给予鲨肝醇片、利可君片口服治疗,治疗组给予神阙、气海、关元、足三里穴位艾灸治疗,比较2组治疗前后中医症候评分、KPS评分和外周血白细胞计数,并比较治疗后2组白细胞计数正常率和治疗总有效率。结果:治疗后治疗组中医症候评分低于对照组,KPS评分高于对照组,治疗组外周血白细胞计数、白细胞计数正常率和治疗总有效率高于对照组,差异均有统计学意义(P<0.05,P<0.01)。结论:穴位艾灸可有效改善了患者气阴两虚的中医症候,提高了患者的功能状态和体力状况,升高外周血的白细胞计数,治疗肿瘤化疗后白细胞减少疗效显著。

Objective： To explore the clinical effect of acupoint moxibustion in the treatment of leukocytopenia caused by tumor chemotherapy. Methods： Eighty two patients with leukocytopenia caused by tumor chemotherapy admitted to our hospital from January 2013 to June 2015 were divided into two groups according to the random number table,with 41 cases in each group. The control group was given Batilol tablets,Leucogen tablets for oral treatment,and the study group was given moxibustion on Shenque,Qihai,Guanyuan,Zusanli acupoint. TCM symptoms score,KPS score and peripheral blood white cell count before and after treatment were compared between the two groups,and white blood cell count normal rate and total effective rate of the two groups were compared. Results： TCM symptom score of the treatment group was lower than that of the control group,and its KPS score was higher than that of the control group,the peripheral blood white blood cell count and the total effective rate of the treatment group were significantly higher than those of the control group,and all the differences were statistically significant（P〈 0. 05,P 〈0. 01）. Conclusion： Moxibustion can effectively improve both Qi and Yin deficiency syndrome of the patients and improve the patient＇s functional status and physical condition,increase the peripheral blood white cell count,and it has a distinct curative effect in treatment of leukopenia due to tumor chemotherapy.