阻塞性睡眠呼吸暂停儿童内皮功能障碍与血浆脂蛋白相关磷脂酶A2活性升高相关

Endothelial dysfunction in children with obstructive sleep apnea is associated with elevated lipoprotein-associated phospholipase A2 plasma activity levels

阻塞性睡眠呼吸暂停（obstructive sleep apnea,OSA）是高度流行的病症,特别是在肥胖儿童中。与作为动脉粥样硬化前期表现的内皮功能障碍和血脂异常的风险增加有关。脂蛋白相关磷脂酶A2（lipoprotein-associated phospholipase A2,Lp-PLA2）被认为是心血管病风险和动脉粥样硬化斑块活动的独立危险因素。