大脑中动脉狭窄程度及侧支代偿与神经功能缺损的关系

The Relationship Between the Degree of Middle Cerebral Artery Stenosis and Collateral Compensation

目的探讨大脑中动脉狭窄程度及侧支代偿与神经功能缺损的关系。方法经磁共振血管成像(MRA)、经颅多普勒超声(TCD)确诊的大脑中动脉狭窄(其为责任血管)的急性脑梗死患者60例,分为轻度狭窄、中-重度狭窄组,采用经颅多普勒(TCD)评估侧支代偿情况,将中-重度狭窄组再次分为侧支代偿组及未代偿组。进行美国国立卫生研究院卒中量表(NIHSS)评分来评估神经功能缺损程度。结果 (1)轻度狭窄组与中-重度狭窄组NIHISS评分差异无统计学意义。(2)侧支代偿组与无侧支代偿组NIHISS评分差异有统计学意义。结论侧支代偿与神经功能缺损程度有密切的关系。

Objective To investigate the relationship between the degree of middle cerebral artery stenosis and the collateral circulation with the neurological impairment. Methods We selected 60 patients with acute cerebral infarction who were diagnosed as cerebral artery stenosis （which is responsible vessels）, based on magnetic resonance angiography （MRA） and transcranial Doppler ultrasound （TCD）. By TCD assessment of collateral circulation, cerebral patients were divided into mild stenosis group and severe stenosis group. The severe stenosis group were further divided into collateral compensatory group and non compensatory group. The National Institutes of Health Stroke Scale （NIHSS） score was used to assess the degree of neurologic impairment. Results （1） There was no significant difference in NIHISS score between the mild stenosis group and the severe stenosis group. （2） There was significant difference in NIHISS score between the collateral compensation group and non collateral compensation group. Good collateral compensation can reduce the degree of neurological impairment. Conclusion There is a close relationship between collateral colnpensation and the degree of neurological impairment.