广泛气道MRSA感染误诊为毛霉菌病1例并文献复习

Inhaled methicillin resistant staphylococcus aureus infection misdiagnosed as Mucormycosis：a case report and review of literature

目的 通过对1例耐甲氧西林金黄色葡萄球菌（MRSA）感染误诊为毛霉菌病病例的分析,增强对MRSA感染及毛霉菌病的认识.方法 报道2016年4月16日西京医院呼吸与危重症科收治的1例误诊为毛霉菌病的MRSA感染病例并结合相关文献进行复习.结果 广泛气道感染MRSA较少见,起病急,进展快,主要表现为咳嗽、咳痰、发热及呼吸困难,而毛霉菌病与其存在高度相似性,二者均易出现在免疫缺陷人群,容易误诊.结论 充分认识MRSA及毛霉菌致病特点,对可疑病例应积极行细菌涂片、培养及组织病理学,并及时行支气管镜下检查及治疗.

Objective To acquire a understanding of methicillin resistant staphylococcus aureus （MRSA） infection and mucormycosis from a misdiagnosed patient.Methods A case of infection with MRSA misdiagnosed as mucormycosis was retrospectively analyzed and the related literature was reviewed.Results Patients with extensive MRSA infenction of respiratory tract,such as cough,expectoration,fever and shortness of breath,was similar to these with mucormycosis.Both infections occured in the immunocompromised population,onset acut and progress fast,and easy to bemisdiagnosed.Conclusions Understanding the character of the MRSA infection and mucormycosis can decrease the misdiagnose rate,and sputum smear、culture and histopathological examination can improve diagnosis rate.Bronchscope is very necessary and important,especially in the early identification and treatment of the infections.