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粪菌移植治疗儿童炎症性肠病 被引量:5

Fecal microbiota transplantation in treatment of inflammatory bowel disease in children
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摘要 炎症性肠病(IBD)是一组病因尚不明确的慢性复发性非特异性肠道炎症性疾病,越来越多的证据表明,肠道微生态失衡在IBD发病中起重要作用。粪菌移植通过重建肠道菌群治疗微生态失衡相关性疾病,在临床已显现疗效,现主要阐述粪菌移植在儿童IBD中的应用。 Inflammatory bowel disease (IBD) is a group of chronic, relapsing and nonspecific intestinal inflammatory diseases of unknown etiology. More and more evidence indicated that the intestinal microflora might play an important role in the pathogenesis of IBD. Fecal microbiota transplantation (FMT) has been used in intestinal flora imbalance related diseases and achieved favorable results. This article mainly reviewed the application of FMT in the treatment of children with IBD.
作者 黄瑛 王玉环
出处 《中华实用儿科临床杂志》 CSCD 北大核心 2017年第7期491-493,共3页 Chinese Journal of Applied Clinical Pediatrics
关键词 粪菌移植 肠道菌群 炎症性肠病 儿童 Fecal microbiota transplantation Intestinal microflora Inflammatory bowel disease Child
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  • 1Guarner F, Maiagelada JR. Gut flora in health and disease[J]. Lancet, 2003, 361(9356): 512-519.
  • 2Eckburg PB, Bik EM, Bernstein CN, et al. Diversity of the human intestinal microbial flora [J]. Science, 2005, 308 (5728) : 1635-1638.
  • 3Borody TJ, Campbell J. Fecal microbiota transplantation: tech- niques, applications, and issues[J]. Gastroenterol Clin North Am, 2012, 41(4): 781-803.
  • 4Surawicz CM, Brandt LJ, Binion DG, et al. Guidelines for di- agnosis, treatment, and prevention of Clostridium difficile in- fections[J]. Am J Gastroenterol, 2013, 108 (4): 478-498. quiz 499.
  • 5Borody TJ, Warren EF, Leis S, et al. Treatment of ulcerative colitis using fecal bacteriotherapy[J]. J Clin Gastroenterol, 2003, 37(1) :42-47.
  • 6Vrieze A, Van Nood E, Holleman F, et al. Transfer of intes- tinal microbiota from lean donors increases insulin sensitivity in individuals with metabolic syndrome[J]. Gastroenterology, 2012, 143(4):913-916.
  • 7e7. Finegold SM, Molitoris D, Song Y, et al. Gastrointestinal mi- croflora studies in late-onset autism[J]. Clin Infect Dis, 2002, 35(Suppl 1) : $6-S16.
  • 8Kelly CR, Kahn S, Kashyap P, et al. Update on fecal microbiota transplantation 2015: Indications, methodologies, mechanisms, and outlook[J]. Gastroenterology, 2015, I49(1): 223-237.
  • 9Youngster I, Russell GH, Pindar C, et al. Oral, capsulized, frozen fecal microbiota transplantation for relapsing Clostridi- um difficile infection[J]. JAMA, 2014, 312(17) : 1772-1778.
  • 10Persky SE, Brandt LJ. Treatment of recurrent Clostridium dif- fieile-associated diarrhea by administration of donated stool di- rectly through a colonoscope[J]. Am J Gastroenterol, 2000, 95(11) : 3283-3285.

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