子痫前期患者产后期眼动脉血流动力学改变的研究

Study on the hemodynamic changes of the ophthalmic artery in patients with preeclampsia

目的:探讨子痫前期患者产后期眼动脉的血流动力学改变。方法:选取30例无合并症单胎妊娠孕妇为对照组,32例子痫前期孕妇作为研究组。应用彩色多普勒超声分别于产后10d(T1期)、产后11~42d(T2期)测量研究组眼动脉的阻力指数(RI)、搏动指数(PI)以及峰值比率(PR),并比较不同时间点各血流动力学指标,及T1期两组眼动脉的各血流动力学指标。结果:T1期两组患者眼动脉的RI、PI、PR值比较差异均有统计学意义(均P<0.05);研究组T1期与T2期各血流动力学指标比较差异均有统计学意义(均P<0.05),而研究组T2期各血流动力学指标与对照组比较无明显差异(P>0.05)。结论:子痫前期患者T1期眼动脉仍持续扩张,眼眶区域仍处于高灌注状态;但是T2期眼动脉的各血流动力学指标基本恢复正常。

Objective：To investigate the hemodynamic changes of the ophthalmic artery during the postpartum period of preeclampsia. Methods： 30 cases of singleton pregnancy without complications were selected as the control group and 32 preeclamptic pregnant women as the research group. The resistance index （RI）, pulsation index （PI） and peak ratio （PR） of the ophthalmic artery in the research group were measured by color Doppler ultrasound at 10 days postpartum （T1） and 11-42 days postpartum （T2）. The hemodynamic indexes of the ophthalmic artery in the control group were measured at 10 days postpartum and compared with those of the research group. Results： There were significant differences in the RI, PI and PR values of the ophthalmic artery between the two groups （ P 〈0.05）. There were significant differences in all hemodynamic indexes between T1 and T2 in the research group （ P 〈0.05）, but no significant difference in hemodynamics at T2 between the two groups （ P 〉0.05）. Conclusion： The ocular artery continues to dilate and the orbital region was still in high perfusion state within 10 days postpartum. However, the hemodynamic indexes of the ocular artery in 11-42 days after delivery had backed to normal.