影响婴幼儿肠道微生物定植的相关因素的研究进展

Research Progress of the Related Factors Influencing the Infant Gut Microbial Colonization

婴幼儿肠道微生物菌群的形成从胎儿期开始延续到2~3岁,是个动态过程。早期肠道微生物与宿主间的相关作用对人类健康发育及新陈代谢具有重要作用。遗传、环境、胎龄、分娩方式、喂养方式、断奶、使用抗生素、益生菌等都可影响肠道微生物定植。

Development of the infant gut microbiota is a dynamic process that begins prenatally and continues during the first two to three years of life. Interactions between the commensal bacteria and the host in the early postnatal period are important for metabolism and healthy development of human. There are many factors, such as host genetics, environmental factors, gestational age, mode of delivery, diet, weaning, antibiotic use and probiotics, can influence microbial colonization in infants.