α-细辛脑注射剂的研究进展与临床应用

Research progress and clinical application of α-asarone injection

目的了解α-细辛脑注射剂的研究与临床应用概况。方法从药理毒理、制剂及质量控制、临床应用和不良反应等方面进行文献搜集和综述。结果α-细辛脑注射剂在止咳、平喘等方面具有较强的作用,但产品质量参差不齐,不良反应发生较多,且毒理作用有待进一步研究。结论α-细辛脑注射剂在临床上具有一定疗效,但其相应的不良反应报道也逐渐增多,其毒理还有待进一步研究,其产品的质量标准体系和说明书也有待进一步完善。

Objective To understand the current state of research and clinical application of α-asarone injection.Method Literature search was conducted and the pharmacology,toxicology,preparation,clinical application and adverse reactions of α-asarone were reviewed.Results α-asarone injection has strong relieving effects on cough and asthma,but the quality of production is varying,adverse reactions are often reported,and the toxicological effects need to be further investigated.Conclusions α-asarone injection has a certain clinical effect,but the reports of related adverse reactions are gradually increased.Its toxicity remains to be further studied,and the product quality standard system and instructions need also to be further improved.