徐州农村地区胃癌高危人群干预效果分析

Intervention efficacy of gastric cancer high-risk population from rural areas of Xuzhou City

目的:评价农村胃癌高危人群综合干预措施的效果。方法:从徐州农村地区选择胃癌高危人群257人进行干预。干预措施包括药物干预和行为干预。干预6个月之后,利用调查问卷收集资料,评价胃癌防治知识及胃癌预测因素的变化。干预1 a后,89人复查幽门螺杆菌感染,111人复查胃镜,依据复查结果评价幽门螺杆菌感染和胃部疾病改善情况。结果:干预后,三餐规律性、腌制食物食用频率、辛辣食物食用习惯、每月食盐量、饮酒习惯等因素较干预前有改善(P<0.05);幽门螺杆菌感染率由干预前的58.4%下降到干预后的40.4%(P=0.002),好转20人(22.4%),无效65人(73.0%),加重4人(4.5%)。胃镜检查结果好转34人(30.6%),无效77人(69.4%)。结论:对农村胃癌高危人群实施行为干预和药物干预,可以提高人群的胃癌防治知识水平,有效控制胃癌前疾病的发生发展。

Aim： To assess the intervention efficacy of the gastric cancer high-risk population from rural area of Xuzhou City. Methods： A total of 257 cases intervened by medical and behavior intervention were followed up through telephone in Xuzhou City. After 6 month intervention,data were collected by questionnaire survey,and the changes of the awareness of prevention knowledge about gastric cancer and cancer risk factors were evaluated. After 1 a,111 cases were under went the endoscopy and 89 were reviewed for Hp infection,and the situation of improvement of gastric diseases were assessed. Results： The survey revealed that regular meals,pickled food consumption frequency,spicy food eating habits,daily salt consumption,and drinking habits of the villagers had been improved（ P〈0. 05）. Hp-infected rate was reduced from 58. 4% to 40. 4%（ P = 0. 002）,with improved in 20 cases,ineffective in 65 cases,and aggravated in 4 cases. The results of endoscopy showed that the symptoms improved in 34 cases and not improved or progressed in 77 cases. Conclusion： Implementation of behavioral intervention and drug intervention in rural high-risk population of gastric cancer can effectively improve the gastric cancer prevention and control knowledge,so that prevent and control the occurrence and development of gastric precancerous diseases.