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帕金森病与肌萎缩侧索硬化发病机制的共性研究 被引量:4

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摘要 帕金森病(PD)与肌萎缩侧索硬化(ALS)同属于神经系统退行性疾病的范畴,目前认为二者发病机制都与基因和环境有关。虽然临床表现不同,但是随着对二者发病机制的深入研究,大量的研究资料表明,二者发病机制上存在许多共性。本文主要围绕共同的兴奋性毒性、免疫/炎症反应、金属毒性、线粒体、细胞自噬、外泌体功能障碍及血管内皮功能障碍等方面分析PD与ALS在发病机制上的共性,
出处 《中国老年学杂志》 CAS 北大核心 2017年第7期1818-1820,共3页 Chinese Journal of Gerontology
基金 国家自然科学基金资助项目(30560042 81160161 81360198)
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