表面分子印迹传感器的应用研究进展

Progress in Applications of Surface Molecular Imprinting Sensors

基于表面分子印迹技术发展起来的表面分子印迹传感器具有与生物传感器相媲美的选择识别性,同时还兼具易于制备、成本低廉、机械稳定性高和重复性好的优点,受到了国内外研究者的极大关注。与传统的气相、气-质、液相、液-质等色谱分析方法相比,表面分子印迹传感器集分离与测试于一体,不需要任何样品前处理步骤,因此测试更加简单、灵敏和快速,在药物传输、环境监测、食品安全、化学反应实时监测等方面获得广泛应用。本文综述了表面分子印迹传感器的分类、制备方法和应用领域,以及该技术面临的挑战和市场应用前景及未来趋势,为相关科研工作者提供研究参考。

Surface moleeular imprinted sensors （SMIS） have comparable selectivities with those biosensors. They have received great attention from domestic and foreign researchers due to the advantages of easy preparation, low cost, remarkable robustness and excellent repeatability. Compared with the traditional chromatography analysis methods （i. e. , GC, GC-MS, HPLC and HPLC-MS etc. ） , SMIS combine separation and detection functions without any sample pretreatment step, so they can afford a much simple, sensitive and rapid sample analysis, and are widely used in medicine transferring, environmental monitoring, food safety analysis and real-time chemical analysis. In this paper, the classification, fabrication methods and application fields of SMIS are reviewed, and the challenges and prospects of this technology are also discussed.