摘要
随着MSCT技术的发展和低剂量CT筛查的广泛应用,多原发肺癌(MPLC)检出率逐年升高,尤其是越来越多表现为磨玻璃密度(GGO)的MPLC被检出。但目前的临床病理诊断标准、分子遗传学技术及处理原则尚不能满足MPLC的个体化需求。本文旨在对MPLC的诊断、雌激素浓度与同时MPLC(SMPLC)的相关性、MPLC的分子遗传学研究及管理策略进行综述。
With the development of MSCT and the widely applications of low-dose CT screening for lung cancer, the incidence of multiple primary lung cancer （MPLC）, especially for which is characterized by ground glass opacity （GGO）. However, the current clinicopathological criteria, molecular genetic technology and management strategies can not meet the needs of individualized demand. The latest progresses in the diagnostic aspects of MPLC, estrogen concentration in synchronous MPLC, molecular genetic characteristics, and management strategies of MPLC were reviewed in this paper.
出处
《中国医学影像技术》
CSCD
北大核心
2017年第4期620-623,共4页
Chinese Journal of Medical Imaging Technology
基金
中国人民解放军总医院临床科研扶持基金(2016FC-TSYS-1025)
关键词
肺肿瘤
突变
雌激素
诊断
处理策略
Lung neoplasms
Mutation
Estrogen
Diagnosis
Management strategies
