应用整合医学理念认识烧伤脓毒症的防治

Recognizing prevention and treatment of burn sepsis with the concept of holistic integrative medicine

尽管基础研究和临床治疗技术不断提高，感染和脓毒症的病理生理机制并不十分清楚。严重烧伤合并脓毒症的病情凶险，治疗难度大，病死率高。更全面地了解烧伤感染的危险因素，分析综合治疗的有效性，对于提高严重大面积烧伤的治疗水平具有重要意义。整合医学是近年来逐渐受到重视的医学体系，从人的整体出发，整合利用医学各领域最先进的知识理论和临床有效的实践经验，对某种疾病或病症进行综合判断分析和处理[1]。严重大面积烧伤和烧伤脓毒症具有错综复杂的病理生理改变，无论是诊断还是治疗都需要从整体出发。本文着重讨论整合医学理念在烧伤脓毒症发病机制和综合治疗等中的应用。

Sepsis remains a major cause of death in severe burns. The effect of sepsis management is influenced by its complicated pathophysiologic changes. In order to improve the outcome of burn sepsis, the predisposing factor of sepsis after burn analyzed by advanced technology, the early prevention, antibiotics therapy, and combined treatment in severe burns with sepsis are discussed using the concept of holistic integrative medicine.