尤瑞克林联合曲克芦丁对急性脑梗死患者凝血功能及神经功能的改善作用研究

Study on the Improvement of Coagulation and Neurological Function in Patients with Acute Cerebral Infarction by Combination of Ulinacin and Trichostatin

目的分析尤瑞克林联合曲克芦丁对急性脑梗死患者凝血功能和神经功能的改善作用。方法选取东海县人民医院2014年6月—2016年6月收治的急性脑梗死患者70例,随机分为对照组34例和观察组36例。对照组患者给予单独尤瑞克林治疗,观察组患者给予尤瑞克林联合曲克芦丁治疗。连续治疗3周,比较两组患者治疗前后血小板计数、纤维蛋白原、D-二聚体、神经功能缺损评分量表(NIHSS)评分。结果观察组治疗后血小板计数、纤维蛋白原、D-二聚体均低于对照组,差异有统计学意义(P<0.05)。观察组治疗后NIHSS评分低于对照组,差异有统计学意义(P<0.05)。结论曲克芦丁联合尤瑞克林治疗急性脑梗死患者能有效改善患者的凝血功能及神经功能,效果显著。

Objective To study the improvement of coagulation and neurological function in patients with acute cerebral infarction by combination of ulinacin and trichostatin. Methods 70 patients with acute cerebral infarction in Donghai County people’s Hospital from June 2014 to June 2016 were selected,and randomly divided into control group（ n = 34） and observation group（ n = 36）. Control group were treated with Yuri Clinton alone treatment,observation group were treated with troxerutin treatment Yuri klein. After 3 weeks of treatment,the platelet count,fibrinogen,D-dimer and neurological deficit score（ NIHSS） score were compared between the two groups before and after treatment. Results After treatment,the platelet count,fibrinogen and D-two in the observation group were lower than those in the control group,the difference was statistically significant（ P 〈 0. 05）. After treatment,the NIHSS score of the observation group was lower than that of the control group,the difference was statistically significant（ P 〈 0. 05）. Conclusion Yuri Klein troxerutin combined treatment of acute cerebral infarction patients can effectively improve the blood coagulation function and nerve function of patients,the effect is significant.