神经外科术后颅内感染因素及预防策略分析

Analysis of Postoperative Intracranial Infection Factor and Preventive Strategies in the Department of Neurosurgery

目的分析神经外科术后颅内感染诱发因素及对应的应对措施。方法整群选取2008年12月—2015年12月7年间在该院神经外科就诊的912例开颅手术患者临床资料进行分析,将54例发生颅内感染的患者作为实验组,其余858例患者作为对照组;并统计分析两组患者术前、术中以及术后相关诱发因素。结果发生颅内感染患者有54例,颅内感染率为5.92%;实验组患者术前合并症34例显著高于对照组的29例,差异有统计学意义(P<0.05);实验组患者术前CGS评分(7.81±1.12)分,显著的低于对照组的(8.48±1.34)分,差异有统计学意义(P<0.05);实验组患者的平均手术次数(1.33±0.31)次、术中的出血量(451.8±57.4)m L以及手术进行时间(4.36±0.64)h,均显著的高于对照组患者,差异有统计学意义(P<0.05);两组患者急诊手术占比差异无统计学意义(P>0.05)。结论引发神经外科术后颅内感染的因素较多,所以对神经外科颅脑手术患者采取一定的预防措施及及时治疗,有助于降低术后颅内感染的发病风险,改善预后效果。

Objective To analyze the postoperative intracranial infection factor and preventive strategies in the department of neurosurgery. Methods Group selection 912 cases of patients with craniotomy treated in the department of neurosurgery in our hospital from December 2008 to December 2015 were selected and divided into the experimental group with 54 cases and the control group with 858 cases, and the preoperative, intraoperative and postoperative related causes of the two groups were counted and analyzed. Results There were 54 cases with intracranial infection, and the intracranial infection rate was5.92%, and the incidence rate of preoperative complications in the experimental group was obviously higher than that in the control group（34 cases vs 29 cases）, and the difference had statistical significance（P〈0.05）, and the preoperative CGS score in the experimental group was obviously lower than that in the control group[（7.81±1.12）scores vs（8.48±1.34）scores], and the difference had statistical significance, and the average operation time, intraoperative bleeding amount and operative time in the experimental group were respectively（1.33±0.31）times,（451.8±57.4）m L and（4.36±0.64）h, and the difference had statistical significance（P〈0.05）, and the difference in the emergency operation between the two groups had no statistical significance（P〉0.05）. Conclusion The cause of postoperative intracranial infection in the department of neurosurgery is more, therefore, a certain preventive measures and timely treatment for patients with intracranial infection in the department of neurosurgery contributes to reducing the incidence risks of postoperative intracranial infection and improve the prognosis effect.