分析不同孕周重度子痫前期对母婴结局的影响

To analyze the effects of severe preeclampsia at different gestational weeks on maternal and neonatal outcomes

目的:观察不同孕周重度子痫前期患者母婴结局,为以后的临床诊治提供参考依据。方法:选取2013年1月至2016年5月我科室诊治的60例重度子痫前期患者,对其资料进行回顾性分析,根据发病时孕周不同分组,将发病孕周≤34周,即早发型重度子痫前期者列为A组,发病孕周>34周即晚发型重度子痫前期者列为B组,分析各组患者的治疗情况、并发症及母婴结局。结果:B组产前并发症发生率低于A组,子痫、肝肾损伤、胎盘早剥、产后出血并发症发生率组间比较差异有统计学意义(P<0.05),心衰、Hellp综合征并发症发生率组间比较差异无统计学意义(P>0.05);两组孕妇均无死亡病例,分娩方式间比较差异有统计学意义(P<0.05),新生儿结局中新生儿窒息发生率比较差异有统计学意义(P<0.05),新生儿死亡率间比较差异无统计学意义(P>0.05)。结论:不同孕周重度子痫前期患者对孕妇及新生儿结局影响不同,发病孕周越早,孕妇产前并发症越多,新生儿预后越差。

Objective:To observe the maternal and neonatal outcomes of severe preeclampsia in different gestational weeks,and to provide reference for clinical diagnosis and treatment.Methods:We selected 60 patients with severe preeclampsia in my department from January 2012 to May 2016,The data were retrospectively analyzed,according to the different gestational age group,the incidence of gestational age less than 34 weeks,the early onset of severe preeclampsia were classified as group A,the incidence of gestational age>34weeks late onset severe preeclampsia were classified as group B,were analyzed in patients with treatment,complications and maternal the ending.Results:B group prenatal complication rate was lower than that of A group,eclampsia,liver and kidney damage,placental abruption,postpartum hemorrhage rate of complications were statistically significant difference(P < 0.05),heart failure,Hellp syndrome complication rate was no significant difference between groups(P >0.05);the two groups of pregnant women were no deaths,there were the significance of the difference between the mode of delivery(P <0.05),neonatal asphyxia in neonatal outcome rate was statistically significant(P <0.05),there was no significant difference between the neonatal mortality rate(P >0.05).Conclusion:The patients with severe preeclampsia at different gestational weeks had different effects on the outcomes of pregnant women and neonates.The earlier the gestational age was,the more complications of pregnant women,the worse the prognosis.