摘要
目的观察平眩方对椎动脉型颈椎病(痰瘀阻络证)的临床疗效和安全性。方法将60例椎动脉型颈椎病患者随机分为观察组和对照组,每组30例。观察组采用平眩方治疗,对照组采用颈复康颗粒治疗,两组均治疗四周,并随访半年。观察两组治疗前后临床总有效率、临床症状分级评分改变、经颅多普勒检查血流参数的改变;并在治疗期间观察有无治疗相关不良反应等情况。结果观察组总有效率为90.0%,对照组总有效率为86.6%,两组无统计学差异(P>0.05)。两组治疗后临床症状积分均降低(P<0.05),治疗后两组间比较,无统计学差异(P>0.05)。经颅多普勒检查,两组治疗后VA、BA的Vs、Vd值升高(P<0.05),观察组与对照组比较,差异具有统计学意义(P<0.05)。结论运用平眩方治疗椎动脉型颈椎病(痰瘀阻络证)疗效确切、复发率低,其总有效率、临床症状分级评分改善与颈复康组疗效相当,TCD指标改善及远期疗效优于对照组,是一种值得临床推广的治疗椎动脉型颈椎病的有效方法。
Objective To observe the clinical efficacy and safety of Pingxuan Prescription in treating vertebral artery type of cervical spondylosis(phlegm and blood stasis). Methods 60 patients with vertebral artery type of cervical spondylosis were randomly divided into the observation group and control group, 30 cases in each group. Patients in the observation group were treated with Pingxuan prescription and patients in control group were treated with Jingfukang granule. Two groups were treated for four weeks and followed up for half a year. Total clinical effective rate, clinical symptom score, changes of transcranial Doppler ultrasound blood flow parameters and related side effects were observed before and after treatment classification in both groups, separately. Results The total effective rate was 90% in case group and 86.6% in control group. There is no statistical significant between the two groups(P〈0.05). The clinical symptom scores of both the two groups were decreased(P〈0.05). There was no statistical significant between the two groups after treatment(P〈0.05). VA, BA Vs, Vd of the two groups increased in TCD after treating(P〈0.05). While the differences between the two groups were not significant(P〈0.05). Conclusion Ping Xuan decoction in treating vertebral artery type of cervical spondylosis(phlegm and blood stasis)shows curative effect, low recurrence rate. The total effective rate and clinical symptoms grading score improvement are simil lar with those in Jingfukang group. TCD indicators improvement and long-term curative effect are better than that of control group. It is an effective method for treatment of vertebral artery type of cervical spondylosism, worthy of clinical promotion.
出处
《湖南中医药大学学报》
CAS
2017年第3期336-339,共4页
Journal of Hunan University of Chinese Medicine
关键词
椎动脉型颈椎病
平眩方
痰瘀阻络证
vertebral artery type of cervical spondylosis
Pingxuan prescription
syndrome of phlegm and blood stasis