复方升白颗粒提取工艺研究

Study on Extraction Process of Compound Shengbai Granule

目的:探讨最优的复方升白颗粒提取工艺。方法:采用正交设计实验,以马钱苷提取率,2,3,5,4,-四羟基二苯乙烯苷-2-O-β-D-葡萄糖苷提取率及提取物干膏得率为指标,优化提取工艺。结果:正交设计实验结果显示最优提取工艺为药材加6倍的水煎煮3次,每次2h。结论:本提取工艺能最大限度地提取出药材的有效成分,节能、省时、不污染环境,适宜工业化可持续生产。

Objective： To seek the best extraction process of Compound Shengbai Granule. Methods： Orthogonal design was used to optimize the best extraction process with the detection targets such as extraction rates of loganin,and 2,3,5,4,- Terahydroxystilbene- 2- O- β- D- Glucoside. Results： Orthogonal experiment showed the best extraction process was to boil the material 3 times,each with 6 times water for 2 hours. Conclusion： The extraction process can highly extract the effective component as well energy- save,time- save and not pollute the environment,which is suitable for industrial mass production.