经皮肾镜下超声气压弹道碎石机与钬激光碎石机在复杂性肾结石治疗中的应用研究

A research: therapeutic application of pneumatic ballistic lithotripsy under percutaneous nephroscope ultrasound and holmium laser lithotripsy for complex renal calculus

目的:探讨经皮肾镜下超声气压弹道碎石机与钬激光碎石机在复杂性肾结石的治疗应用效果。方法:选择医院收治的124例复杂性肾结石的患者,采用随机数字表法将其分为观察组和对照组,每组62例。观察组采用经皮肾镜超声气压弹道碎石术治疗,对照组采用钬激光治疗,对比两组患者术中、术后等相关指标、术后并发症的发生情况以及肾功能等相关指标。结果:两组术中出血量、术后住院时间比较,差异有统计学意义(t=12.475,t=7.659;P<0.05),两组结石清除率、并发症发生率比较,差异有统计学意义(x^2=6.048,x^2=7.159,P<0.05);两组患者在治疗后肾盂集合系统分离指数、肌酐和尿素氮比较差异均有统计学意义(t=8.529,t=7.058,t=10.596;P<0.05)。结论:经皮肾镜超声气压弹道碎石术治疗治疗复杂性肾结石与传统的钬激光碎石术相比较,其临床效果显著,具有手术时间段、术后恢复较快,对患者安全可靠,并且降低了术后并发症的发生率,可有效的缓解患者的肾功能。

Objective： To explore the effect of therapeutic application of pneumatic ballistic lithotripsy under percutaneous nephroscope ultrasound and holmium laser lithotripsy for complex kidney stone. Methods： 124 patients with complex renal calculus were selected and divided into observation group（62 cases） and control group（62 cases） as randomly number table. The patients of observation group were cured by pneumatic ballistic lithotripsy under percutaneous nephroscope ultrasound while patients of control group were cured by holmium laser lithotripsy. A series of correlative indicators, such as some correlative indexes in during and post operation, complication situation of post operation and kidney function, were compared. Results： The differences about bleeding volume during operation and postoperative hospital stay between the two groups were significant（t=12.475, t=7.659, P〈0.05）. For clearance rate of calculus and incidence of complication, the differences between the two groups were significant（x^2=6.048, x^2=7.159, P〈0.05）. And the differences of separation index of renal pelvis collective system, creatinine and urea nitrogen post treatment between the two groups also were significant（t=8.529, t=7.058, t=10.596, P〈0.05）. Conclusion： Comparing with the traditional holmium laser lithotripsy, the clinical better effect of pneumatic ballistic lithotripsy under percutaneous nephroscope ultrasound for complex renal calculi is significant. Its series of advantages, such as shorter operation time, faster recovery, safer and reliable for patients and lower incidence of postoperative complication and so on, can effectively relieve the renal function for patients.