小剂量阿司匹林治疗高龄稳定型心绞痛的有效性及安全性分析

Analysis of effectiveness and safety of low dose Aspirin in the treatment of elderly patients with stable angina pectoris

目的分析高龄稳定型心绞痛患者口服小剂量阿司匹林治疗的临床效果及安全性。方法对比120例长期口服75 mg、100 mg阿司匹林稳定型心绞痛患者消化道出血事件及急性冠脉综合征发生率,分析有效性及安全性。结果小剂量组与常规剂量组比较,急性冠脉综合征、猝死等发生率相当,消化道出血事件减少,差异均有统计学意义(P<0.05)。结论小剂量阿司匹林治疗高龄稳定型心绞痛,其有效性与常规剂量相当,出血并发症减少,值得临床推广。

Objective To evaluate the efficacy and safety of low dose aspirin in elderly patients with stable angina pectoris, Methods To compare the incidence of acute coronary syndrome and gastrointestinal bleeding in 120 patients with long-term oral 75mg and 100mg aspirin,and to analyze the effectiveness and safety. Results Compared with the conventional dose group, the incidence of acute coronary syndrome, sudden death and other incidence of acute coronary syndrome, the incidence of gastrointestinal bleeding decreased. Conclusion Low dose aspirin in the treatment of stable angina pectoris, its effectiveness is comparable with the conventional dose, reduce bleeding complications, it is worthv of clinical annlication.