绵羊口腔上皮中巯基和二硫基的分布与上皮角化的关系

THE DISTRIBUTION OF SULPHYDRYL AND DISULPHIDE GROUPS IN SHEEP ORAL EPITHELIUM ASSOCIATED WITH KERATINIZATION

对12只绵羊口腔复层扁平上皮中巯基和二硫基分布的研究表明。口腔上皮中的巯基主要分布在有核(非角化)细胞的基质和张力细丝束中,少量存在于所有胞核和角化细胞加厚的质膜内层及角蛋白中。二硫基主要分布在所有胞核和角化细胞加厚的质膜内层及角蛋白中,少量存在于有核细胞的胞质中。透明角质颗粒既不含巯基,又不含二硫基。它们不参与角化过程中加厚质膜的形成。

Twelve sheep were used to siudy the distribution of sulphydryl and disulphide groups in oral stratified squamous epithelium. Most of the sulphydryl groups distributed in matrix and tonofilament bundles of the nucleate(nonkeratinized)cells, and small amounts located in thickened inner leaflet of cell membrane and keratin of the keratinized cells as welll as all nuclei.Disulphide groups distributed mainly in the thickened inner leaflet, keratin and nuclei.Only small amounts of disulphide groups were found in the cytoplasm of nucleate cells. Keratohyalin granules which contained neithed sulphydryl nor disulphide groups were not associated with the formation of thickened inner leaflet of cell membrane.