纸张定量对纸基微流控中溶液扩散的影响

Effect of Basic Weight of Paper on Liquid Penetration in Paper-based Microfluidic Devices

本文研究了纸张定量与亲水通道的宽度对纸基微流控中溶液扩散的影响,同时为纸基微流控中纸张定量的选择提供参考。选用生物检测常用的配比溶液,测量溶液在空白纸、纸条及亲水通道上的扩散长度,得到溶液扩散长度与定量的关系及亲水通道宽度对扩散效率的影响。结果表明溶液扩散长度会随纸张定量的增加而线性减少,溶液扩散效率随亲水通道宽度的增加而增大。纸张定量对溶液的扩散有较大影响,溶液在低定量的纸张上可以实现较长的扩散距离,较宽的亲水通道能获得较大的溶液扩散效率,并能降低溶液在扩散过程中的消耗。

This paper studied the effect of basic weight of paper and width of hydrophilic channels on liquid penetration in paper- based microfluidic devices,and providing reference of the optimal basic weight of paper for paper-based microfluidics. We selected some basic solutions to test the penetration length in untreated paper,slips and hydrophilic channels,and found the relations between basic weight of paper and penetration length of liquids,and the effect of hydrophilic channels on penetration efficiency. Results showed the penetration length of liquid decreased linearly with increasing of basic weight,and efficiency of the liquids increased with increasing of the hydrophilic channels. Basic weight of paper had a great effect on liquid penetration,and low basic weight of paper could achieve a higher penetration length,and wider hydrophilic channels could attain higher penetration efficiency with reducing waste of test liquids in transporting process.