摘要
目的探讨分析沙利度胺治疗克罗恩病的临床疗效。方法 40例克罗恩病患者,按照治疗方法的不同将其分为治疗组及对照组,各20例。对照组给予柳氮磺胺吡啶治疗,治疗组给予沙利度胺治疗。比较两组患者的治疗效果以及不良反应发生率。结果治疗组治疗总有效率为95.0%,高于对照组的70.0%,差异具有统计学意义(P<0.05)。治疗组不良反应发生率为5.0%(1/20),低于对照组的30.0%(6/20),差异具有统计学意义(P<0.05)。结论沙利度胺治疗克罗恩病具有显著的临床疗效,不良反应较少,有利于患者的康复,值得临床推广应用。
Objective To investigate clinical effect by thalidomide in the treatment of Crohn's disease. Methods A total of 40 patients with Crohn's disease were divided by different treatment measures into treatment group and control group, with 20 cases in each group. The control group received salazosulfapyridine for treatment, and the treatment group received thalidomide for treatment. Comparison was made on curative effect and incidence of adverse reactions between the two groups. Results The treatment group had higher total effective rate as 95.0% than 70.0% in the control group, and their difference had statistical significance (P〈0.05). The treatment group had lower incidence of adverse reactions as 5.0% (1/20) than 30.0% (6/20) in the control group, and their difference had statistical significance (P〈0.05). Conclusion Thalidomide shows excellent clinical effect in treating Crohn's disease, along with few adverse reactions. It is beneficial for rehabilitation in patients, and it is worth clinical promotion and application.
作者
罗永灵
陈泽庭
林梓韩
LUO Yong-ling CHEN Ze-ting LIN Zi-han.(Department of Gastroenterology, Guangdong Puning Overseas Chinese Hospital, Puning 515300, China)
出处
《中国实用医药》
2017年第7期114-116,共3页
China Practical Medicine
关键词
沙利度胺
克罗恩病
临床疗效
Thalidomide
Crohn's disease
Clinical effect