深圳市流动人口耐多药肺结核未治愈原因分析

Cause analysis of cureless multi-drug resistant tuberculosis in Shenzhen city floating population

目的探讨深圳市流动人口耐多药肺结核(MDR-TB)患者未治愈原因,提高耐多药肺结核治愈率。方法回顾性分析75例流动人口耐多药肺结核患者未治愈原因。结果未治愈的主要原因:自行中断治疗、丢失、用药不规律、多肺叶病灶伴空洞形成、患者对药物的耐受性差、药物严重不良反应。结论加强健康教育、个体化治疗、采取有效的监控措施、及时处理不良反应等措施,对于提高耐多药肺结核治愈率具有重要意义。

Objective To explore the reason of uncured multi-drug resistant tuberculosis（MDRTB） patients in Shenzhen city floating population, to increase the cure rate of multi-drug resistant tuberculosis. Methods Uncured reasons of multi-drug resistant tuberculosis in 75 cases of floating population were retrospectively analyzed. Results The main cureless reasons were discontinue treatment voluntarily, loss, irregular drug meditation, lung lesions associated with hole formation, poor drug tolerance of patients, serious adverse drug reactions. Conclusion It is important to strengthen health education, individualized treatment, and take effective control measures and timely treatment of adverse reactions, and it has great significance in improving cure rate of multi-drug resistance tuberculosis.