丹红注射液对急性脑梗死患者血尿酸与胆红素水平的影响

Effects of Danhong Injection on the Serum Blood Uric Acid and Bilirubin Levels of Patients with Acute Cerebral Infarction

目的:探究丹红注射液对急性脑梗死患者血尿酸与胆红素水平的影响。方法:选取2015年2月到2016年2月我院神经内科收治的急性脑梗死患者96例,根据随机数字对照表分为对照组与试验组,每组各48例。对照组给予患者钙离子拮抗剂尼莫地平缓释片和抗血小板凝集剂阿斯匹林肠溶片治疗,试验组采用常规药物治疗联合给予丹红注射液治疗。观察并比较两组患者的临床疗效以及治疗前后血尿酸与胆红素水平的变化情况。结果:治疗后,两组患者的NIHSS评分及血尿酸与胆红素水平均较治疗前显著降低(P<0.05),且与对照组相比,试验组的NIHSS评分及血尿酸与胆红素水平更低(P<0.05)。结论:丹红注射液对急性脑梗死患者具有显著的治疗效果,推测可能与降低血尿酸与胆红素的水平有关。

Objective： To investigate the effects of Danhong injection on the serum blood uric acid and bilirubin levels of patients with acute cerebral infarction. Methods： 96 patients with acute cerebral infarction who were treated in the neurology department of our hospital from February 2015 to February 2016 were selected and randomly divided into the control group and experiment group, with 48 cases in each group. Patients in the control group were treated with conventional drugs treatment, including calcium antagonists nimodip- ine sustained release tablets. Patients in the experiment group adopted routine drugs treatment combined with Danhong injection. After treatment, the clinical efficacy, serum blood uric acid and bilirubin levels were compared between two groups. Results： After treatment, the NIHSS scored of the two groups decreased （P〈0.05）, blood uric acid and bilirubinwere lower than before treatment （P〈0.05）; com- pared with the control group, the NIHSS scored of the experiment group significantly reduced, blood uric acid and bilirubin decreased obviously （P〈0.05）. Conclusion： Danhong injection in the treatment of patients with acute cerebral infarction has a obvious effect, specu- late thatis relate to reduce the blood uric acid and bilirubin levels.