辣木黑茶主要药效学研究

An experimental study of main pharmacological effects of Moringa black tea

目的:探讨辣木黑茶的主要药效作用。方法:通过观察辣木黑茶对自由饮食小鼠体质量的影响研究其减肥的功效;通过观察辣木黑茶对小鼠脾指数和胸腺指数的影响研究其调节免疫功能的作用;通过观察辣木黑茶对糖尿病模型大鼠的影响研究其调节血糖的作用;通过观察辣木黑茶对高脂血症模型大鼠的影响研究其调节血脂的作用。结果:辣木黑茶能够显著降低自由饮食小鼠的体质量,且对小鼠免疫功能无影响,与空白组比较,差异有统计学意义(P<0.01);辣木黑茶组小鼠胸腺指数显著升高,与空白组比较,差异有统计学意义(P<0.05);辣木黑茶能够降低糖尿病大鼠血糖值,与模型组比较,差异有统计学意义(P<0.05);辣木黑茶能够显著降低高脂血症大鼠血清TC、TG、LDL水平,与模型组比较,差异有统计学意义(P<0.01或P<0.05)。结论:辣木黑茶具有减肥、降血脂、降血糖等功效。

Objective：To investigate the main pharmacological effects of Moringa black tea. Methods：The slim- ming effect of Moringa black tea was evaluated by observing its effect on the body weight of mice on free diet. The immunoregulatory effect of Moringa black tea was evaluated by observing its effect on the spleen index and thymus index of mice. The blood glucose - regulating effect of Moringa black tea was evaluated by observing its effect on the rat model of diabetes. The blood lipid - regulating effect of Moringa black tea was evaluated by observing its effect on the rat model of hyperlipidemia. Results ： Moringa black tea significantly reduced the body weight of mice on free diet,as compared with the blank group （P 〈 0.01 ）, but had no significant effect on the immune function of mice. The mice in Moringa black tea group had a significantly increased thymus index than the blank group （ P 〈 0. 05 ）. Moringa black tea significantly reduced blood glucose in rats with diabetes, as compared with the model group （P 〈 0. 05 ）. Moringa black tea significantly reduced serum levels of total cholesterol, triglyceride, and low - den- sity lipoprotein in rats with hyperlipidemia, as compared with the model group （ P 〈 0. 01 or P 〈 0. 05 ）. Conclusion ： Moringa black tea has slimming,antihyperlipidemic, and antidiabetic effects.