倍他乐克与稳心颗粒联合治疗心律失常疗效观察

Curative Effect of Betaloc Combined with Wenxin Granules for Arrhythmia

目的:观察倍他乐克与稳心颗粒联合治疗心律失常的临床疗效。方法:研究对象为96例气阴两虚兼心脉瘀阻型心律失常患者,按随机数字表法分为观察组与对照组各48例,观察组给予倍他乐克、稳心颗粒联合治疗,对照组仅给予倍他乐克治疗,比较2组的临床治疗效果,观察治疗前后24 h动态心电图(包括室性早搏、ST段压低及ST段压低持续时间)的变化与不良反应发生情况。结果:治疗后,观察组总有效率91.67%,对照组总有效率72.92%,2组比较,差异有统计学意义(P<0.05)。2组室性早搏次数、ST段压低数值及ST段压低持续时间均较治疗前有所改善(P<0.05),而观察组改善情况优于对照组(P<0.05)。用药治疗期间,观察组不良反应发生率10.42%,对照组不良反应发生率31.25%,2组比较,差异有统计学意义(P<0.05)。结论:倍他乐克与稳心颗粒联合治疗气阴两虚兼心脉瘀阻型心律失常患者临床疗效显著,可有效改善患者的临床症状,且患者的不良反应发生率较低,可作为临床治疗心律失常的常用药物。

Objective：To observe the clinical effect of betaloc combined with Wenxin granules for arrhythmia.Methods Selected 96 cases of patients with arrhythmia of both qi and yin deficiency and heart blood stasis syndrome as study objects,and divided them into the observation group and the control group randomly,48 cases in each group.The treatment group was treated with betaloc combined with Wenxin granules,while the control group was treated with betaloc only.Compared the clinical effect in both groups,and observed changes of 24 hour dynamic electrocardiogram（including ventricular premature beat,ST segment depression and duration of ST segment depression） before and after treatment as well as adverse reaction in two groups.Results：After treatment,the total effective rate was 91.67%in the observation group and 72.92%in the control group,the difference being significant（P〈0.05）.Ventricular premature beat,ST segment depression and duration of ST segment depression in two groups were improved when compared with those before treatment（P〈0.05）,and the improvements in the observation group were superior to those in the control group（P〈0.05）.During treatment,the incidence of adverse reaction was 10.42%in the observation group and 31.25%in the control group,the difference being significant（P〈0.05）.Conclusion：The therapy of betaloc combined with Wenxin granules for patients with arrhythmia of both qi and yin deficiency and heart blood stasis syndrome has evident curative effect.It can effectively improve the clinical symptom.And it causes low incidence of adverse effect among patients,which can be used as the common medicine for the clinical treatment of arrhythmia.