摘要
合成生物学的来临迎来了没有房间的抄写翻译系统的新应用程序。这些没有房间的系统用细胞的蛋白质被重新组成,并且对他们的作文的模块化的控制顺从。这里,我们在合成基因电路和部件的快速的设计讨论没有房间的系统,以及他们的新应用的历史的前进, biomolecules,传染疾病的诊断,和疫苗的合成的指导进化。最后,我们在场我们没有房间的合成生物学的未来方向上的视觉。
The advent of synthetic biology has ushered in new applications of cell-free transcription-translation systems. These cell-free systems are reconstituted using cellular proteins, and are amenable to modular control of their composition. Here, we discuss the historical advance- ment of cell-free systems, as well as their new applications in the rapid design of synthetic genetic circuits and components, directed evolution ofbiomolecules, diagnosis of infectious diseases, and synthesis of vaccines. Finally, we present our vision on the future direction of cell-free synthetic biology.