龙胆泻肝汤治疗偏头痛53例

Treatment of 53 Cases of Migraine by Longdan Xiegan Decoction

目的观察龙胆泻肝汤化裁治疗肝经热盛型头痛疗效。方法使用回顾性设计方法,根据患者治疗期间是否接受中医辨证论治分为对照组和治疗组。对照组28例患者使用钙拮抗剂盐酸氟桂利嗪(商品名:西比灵)治疗,治疗组25例患者使用龙胆泻肝汤化裁治疗。结果治疗组缓解8例,显效9例,好转5例,无效3例,总有效率88%;对照组缓解5例,显效10例,有效5例,无效8例,总有效率为71.43%。两组临床疗效治疗组优于对照组(P<0.05)。结论龙胆泻肝汤化裁治疗肝经热盛型头痛疗效满意,无严重不良反应。

Objective： To observe the effect of modified Longdan Xiegan Decoction on migraine classified into syndrome of heat accumulating in liver channel in TCM. Methods： By designing retrospective methods, the patients were divided into treatment group and control group according to their will whether to accept TCM syndrome differentiation or not. The 28 cases in control group orally took flunarizine hydrochloride （calcium antagonist, Sibelium）, and the 25 cases in treatment were administered modified Longdan Xiegan Decoction. Results： In treatment group, there were 8 cases relieved, 9 cases were with marked effect, 5 improved and 3 ineffective, the total effective rate was 88% ; whereas 5 cases in the control group were relieved, 10 greatly effective, 5 improved and 8 with no effect, as well as the total effective rate was 71.43%. The clinical effect in treatment group was better than that in control group （ P〈0.05 ）. Conclusion： The modified Longdan Xiegan Decoction is greatly effective in treating migraine belonging to the syndrome of heat accumulation in liver channel in TCM and with no serious adverse event.