超声下不同孕周胎儿主要生长参数正常值范围及其生长曲线分析

Analyis on normal reference value ranges of fetal main growth parameters and growth curve during different gestational weeks under ultrasound

目的探讨超声下不同孕周胎儿主要生长参数正常值范围及其生长曲线分析。方法随机选取2014年12月-2015年12月在该院正常足月单胎分娩的产妇1 200例,回顾其应用超声检测的孕17^(+2)周~41^(+5)周共2 711次的主要生长参数:双顶径、头围、腹围和股骨长等,对各项指标与孕周进行相关性分析,以便得出主要生长参数的参考值范围,从而做出生长曲线,并将10年前的研究数据作为对照组。结果与对照组比较,孕27周以后双顶径、腹围和股骨长均呈增高趋势,两者差异有统计学意义(P<0.05);孕37周以后头围基本呈增高趋势,与对照组比较,差异有统计学意义(P<0.05)。对各项指标与孕周进行相关性分析,双顶径、头围、腹围及股骨长与孕周的相关系数r分别为0.968、0.972、0.973、0.979。结论胎儿的双顶径、头围、腹围和股骨长与孕周密切相关,且呈显著正相关,为制定出适合我国胎儿的生长参数标准,有必要更新生长参数正常值范围以及生长曲线。

Objective To explore the normal reference value ranges of fetal main growth parameters and growth curve during different gestational weeks under ultrasound. Methods A total of 1 200 normal pregnant women（ single fetus,full-term pregnancy） were selected from the hospital from December 2014 to December 2015. Biparietal diameter,head circumference,abdominal circumference,and femur length were detected by ultrasound during 17^＋2-41^＋5 weeks for 2 711 times,the correlations between the parameters and gestatinoal week were analyzed,then the reference value ranges were obtained,growth curve was drawn,the study data 10 years ago was summarized as control group. Results Compared with control group,biparietal diameter,abdominal circumference,and femur length after the 27 th gestational week showed increasing trends,there were statistically significant differences（ P〈0. 05）. Head circumstance after the 37 th gestational week showed an increasing trend,compared with control group,there was statistically significant difference（ P〈0. 05）. Biparietal diameter,head circumference,abdominal circumference,and femur length were correlated with gestational week（ r = 0. 968,0. 972,0. 973,0. 979）.Conclusion Fetal biparietal diameter,head circumference,abdominal circumference,and femur length are closely related to gestational age,showing significantly positive correlation. In order to develop growth parameters curve suitable for the fetuses in China,it is necessary to update the normal reference value ranges of fetal main growth parameters and growth curve.