502例注射用灯盏花素超说明书用药分析

Analysis of 502 Cases of Off-label Use of Breviscapine for Injection

目的了解临床注射用灯盏花素超说明书使用情况,为合理使用中药注射剂提供参考。方法对我院2015年1月~12月使用注射用灯盏花素的502例出院患者病历医嘱进行回顾性分析。结果超功能主治用药241例,超剂量用药23例,超浓度用药34例,超给药频次用药7例,于儿童中使用18例。结论临床注射用灯盏花素存在超说明书用药现象,影响患者用药安全,建议严格按照中药注射剂说明书要求合理用药。

Objective To understand the off-label use of breviscapine for injection in clinic, promote reasonable application of traditional Chinese medicine injection. Methods 502 medical records of hospitalized patients using breviscapine for injection in 2015 were retrospectively analyzed. Results There were 241 cases for off-label indications, 23 cases for overdosage, 34 cases for ofF-label concentration, and 7 cases for improper frequency, involving 18 cases in children. Conclusion The off-label use of breviscapine for injection in clinic affects patients5 medication safety. It is suggested that the use of TCM injection should keep in accordance with its instruction strictly.