摘要
真菌对人来说看似"微乎其微",可是其引发的感染大多难以根治。世界卫生组织(WHO)早在2014年发布的《抗菌药物耐药:全球监测报告》就指出因抗生素滥用等因素造成的耐药形式严峻,并且严重地威胁着全球各地人群健康,急需可靠有效的针对真菌所引起的感染的治疗方法。光动力抗真菌治疗方法安全、方便且不易诱导耐药性出现。回顾和总结了近年来光动力抗真菌研究现状,强调了光动力抗真菌治疗方法的优势与潜力。
Fungi belong to microorganism, most of the infections result from fungi are recalcitrant. The publication of World Health Organization （WHO） named 《Antimicrobial Resistance： Global Report on Surveillance》 reports that many factors contribute to grim situation of high level of antifungal drug resistance such as overprescribing antibiotics, which poses a threat to the health of people around the world. There is an urgent need for the development of new and effective therapeutic strategies. Photodynamic therapy （PDT） is an emerging alternative for the inactivation of fungi, it is safe and convenient. In addition, it could decrease fungal resistance potential. We summarize and discuss the effect of PDT against fungus in recent years, and also emphasize the advantages and potential of anti-fungus PDT
作者
李苇
尹锐
LI Wei YIN Rui(School of Bioengineering, Chongqing University, Chongqing 400044, China Department of Dermatology, Southwest Hospital, Third Military Medical University, Chongqing 400038, China)
出处
《激光杂志》
北大核心
2017年第4期1-4,共4页
Laser Journal
基金
国家自然科学基金资助(81571902)
第三军医大学第一附属医院临床创新课题资助(SWH2014LC17)
关键词
光动力治疗
真菌感染
耐药性
photodynamic therapy
fungal infections
drug resistance
