β-隐黄素纳米乳的制备及其稳定性研究

Preparation and stability of β-cryptoxanthin nanoemulsion

以D-柠檬烯为油相,采用低能乳化法制备β-隐黄素纳米乳。对比研究了温度、光照对β-隐黄素纳米乳及β-隐黄素油溶液的影响,以及酸、碱、氧化剂和还原剂对β-隐黄素纳米乳的影响。结果发现:所制备的β-隐黄素纳米乳平均粒径为12.14 nm;β-隐黄素纳米乳比β-隐黄素油溶液更耐热、耐光;短时间强酸强碱环境对β-隐黄素纳米乳稳定性影响较小,但长时间的强酸条件会加速β-隐黄素的降解,而强碱条件会使β-隐黄素纳米乳变浑浊;高浓度的氧化剂会使β-隐黄素纳米乳有轻微降解,而还原剂对β-隐黄素纳米乳具有一定的保护作用。因此,β-隐黄素纳米乳比β-隐黄素油溶液具有更好的稳定性,但仍需避免长时间处于强酸强碱环境。

Nanoemulsion of β-cryptoxanthin was prepared by D-limonene as oil phase. The effect of temperature and light on β-cryptoxanthin nanoemulsion and β-cryptoxanthin oil solution were compared. The effect of acid,alkali,oxidant,reducer to β-cryptoxanthin nanoemulsion was also studied. The results are： average particle size of β-cryptoxanthin nanoemulsion 12. 14nm; β-cryptoxanthin nanoemulsion has better resistance of heat and light; acid and alkali has a little effect of β-cryptoxanthin nanoemulsion in short time; however strong acid accelerated β-cryptoxanthin degradation and strong alkali made β-cryptoxanthin nanoemulsion solution cloudy at long time. High concentration oxidant can cause slightly degradation while reducing agent has certain protection to β-cryptoxanthin nanoemulsion. So,β-cryptoxanthin nanoemulsion has better stability,and needs to avoid in strong acid and alkali.