临床药师干预骨科Ⅰ类切口手术围术期抗菌药物的应用分析

Analysis of Prophylactic Antibiotic Use in Orthopedics Patients Undergoing Type Ⅰ Incision Surgery before and after Intervention

目的通过临床药师干预促进骨科Ⅰ类切口手术围术期的抗菌药物的合理使用。方法临床药师参与骨科Ⅰ类切口手术围术期抗菌药物的管理工作,分别调取干预前、第1阶段干预后、第2阶段干预后骨科Ⅰ类切口手术围术期抗菌药物的使用情况,对药物选择、给药时机、给药时间等进行分析和评价。结果第2阶段干预后,骨科Ⅰ类切口手术围术期抗菌药物预防使用率由84.74%下降至28.27%,第2阶段干预后,抗菌药物使用强度(DDDs)由89.58下降至29.65;抗菌药物的品种选择、给药时间、用药疗程等均趋于合理。结论通过临床药师参与用药管理,医院骨科Ⅰ类切口手术围术期抗菌药物的使用合理性得到了有效改进。

Objective To explore the effectiveness of pharmacists participating in prophylactic use of antibiotics for orthopedic patients undergoing type Ⅰ incision surgery. Methods Clinical pharmacists were involved in the management of on prophylactic use of antibiotics for orthopedic patients undergoing type Ⅰ incision surgery. The effect was evaluated by comparing of the choice of drug selection, delivery timing, and duration time before and after intervention （ first and second stage of intervention ） . Results Compared with pre-intervention, usage rate of antibiotics dropped from 84. 74% to 28. 27%, AUD declined from 89. 58 to 29. 65DDDs. Conclusion Through the above measures, the prophylactic use of antibiotics for orthopedic patients undergoing type I incision surgery is improved greatly.