胸腺五肽注射液不合理用药干预分析

Analysis of the irrational use of thymopentin injection

目的了解我院胸腺五肽注射液的使用现状。方法通过医院信息系统(HIS系统)调取2016年1月至3月首都医科大学附属北京朝阳医院使用胸腺五肽注射液(1 m L/10 mg)的住院病例903例,对其适应证、用法用量、临床疗效、联合用药等进行分析,通过临床药师对问题科室的干预和发布合理用药专项点评通报对不合理之处进行整改。结果经干预后,我院胸腺五肽注射液使用存在使用指征不明确、用法用量及疗程不规范、疗效不确切等问题均得到了明显地改善。胸腺五肽注射液使用量由2016年第1季度的12449支下降至第2季度的10142支。结论临床药师下科室干预和合理用药专项点评是有效的干预措施,临床药师在促进医院合理用药方面具有重要作用。

Objective To investigate the using status of thymopentin injection（ 1 mL/10 mg） in our hospital. Methods Medical records of 903 inpatients receiving thymopentin injection therapy from January to March in 2016 in Beijing Chaoyang Hospital,Capital Medical University were collected from the hospital information system. The indications,dosage,efficacy and combined medication were analyzed and evaluated. Correction was made to the existing problems through the intervention of relative departments by clinical pharmacists and issuing rational drug use bulletin. Results After the intervention,irrational use of thymopentin injection,for examples： indications were not clear,dosage and course of treatment were not standardized or therapeutic effect was equivocal, got obviously improved. The consumption of thymopentin injection in the second quarter dropped to 10142 from 12449 in the first quarter. Conclusion The intervention of clinical pharmacists in wards and issuing rational drug use bulletin are effective measures. Clinical pharmacists play an important role in promoting the rational use of drugs in hospitals.