自拟息风化痰经验方剂内服、推拿联合盐酸乙哌立松片治疗椎动脉型颈椎病的临床研究

Research on Treating Vertebral Artery Type of Cervical Spondylosis Patients with Xifeng Huatan Decoction,Manipulation and Eperisone Hydrochloride Tablets

目的:观察自拟息风化痰经验方剂内服、推拿联合盐酸乙哌立松片治疗椎动脉型颈椎病的临床效果。方法:选择2014年2月—2016年2月本院收治的200例椎动脉型颈椎病患者,随机分为对照组和观察组各100例。对照组患者给予盐酸乙哌立松片治疗;观察组患者则在对照组治疗的基础上给予息风化痰经验方剂内服联合推拿治疗,两组均连续治疗2周。观察患者主要症状改善情况,对证候积分进行评价;用经颅超声多普勒TCD测量患者治疗前后椎动脉血流速度的变化情况,计算有效率。结果:观察组患者的有效率90%与对照组79%相比明显升高,其临床眩晕、颈肩痛、头痛、耳鸣等症状改善尤其明显,证候积分变化明显与对照组比较改善更优,差异有统计学意义(P<0.05);观察组患者的椎动脉血流速度与对照组比较明显升高,差异有统计学意义(P<0.05)。结论:息风化痰经验方剂内服、推拿联合盐酸乙哌立松片治疗椎动脉型颈椎病疗效确切,利于改善患者的临床症状,提高椎动脉血流速度,是中医内外合治颈椎病的突出体现,值得临床推广应用。

Objective：To investigate the clinical efficacy of treating vertebral artery type of cervical spondylosis patients with Xifeng Huatan Decoction, manipulation and eperisone hydrochloride tablets. Methods ： A total of 200 cases were randomly divided into a control group of 100 cases and an observation group of 100 cases from February 2014 to February 2016. Patients in the con- trol group were treated with eperisone hydrochloride tablets while those in the observation group were treated with Xifeng Huatan Decoction and manipulation ,2 weeks for treatment. The paper was aimed at observing the improvement of the main clinical symp- toms, evaluating the syndrome scores, testing the change of vertebral artery blood flow velocity with TCD, and comparing the effec- tiveness. Results ：The clinical effect rates of observation group and control group after treatment were respectively 90% and 79% , and the improvement of symptoms for patients in the observation group was more obvious than that of the control group, and the change of syndrome scores was better than that of the control group. The difference was significant（ P 〉 0.05 ）. The vertebral artery blood flow velocity for patients in the observation group was higher than that of the control group and the difference was significant （ P 〉 O. 05 ）. Conclusion ： Treating vertebral artery type of cervical spondylosis patients with Xifeng Huatan Decoction, manipulation and Eperisone Hydrochloride Tablets has the satisfactory clinical effect. The therapy can effectively alleviate the symptoms and im- prove the vertebral artery blood flow velocity,which highlighted the advantages and characteristics of treating cervical spondylosis with inside and outside of traditional Chinese medicine ,worth of wide application in the clinical practice.