美托洛尔治疗风湿性心脏病慢性心力衰竭的效果分析

Analysis on effect of metoprolol in treatment of rheumatic heart disease complicated with chronic heart failure

目的:分析应用美托洛尔治疗风湿性心脏病慢性心力衰竭的效果。方法:选取我院收治的风湿性心脏病慢性心力衰竭患者100例作为观察对象,按照随机数字表法分为观察组和对照组各50例,其中对照组给予马来酸依那普利片治疗,观察组在对照组基础上联合美托洛尔治疗,观察两组临床治疗效果、心功能指标、舒张压、心率以及心功能分级情况。结果:观察组总有效率(78.00%)显著高于对照组(58.00%)(P<0.05);治疗后两组LVEDD、LADD、LVESD显著低于治疗前(P<0.05),且观察组显著低于对照组,LVEF显著高于治疗前(P<0.05),且观察组显著高于对照组(P<0.05);治疗后两组舒张压、心率、收缩压显著低于治疗前(P<0.05),且观察组显著低于对照组(P<0.05)。结论:采用美托洛尔治疗风湿性心脏病慢性心力衰竭可有效改善患者心功能,提高临床治疗效果。

Objective ：To analyze the effect of metoprolol in treatment of rheumatic heart disease complicated with chronic heart failure.Methods：100 cases of patients with rheumatic heart disease complicated with chronic heart failure treated in our hospital were selected as the study objects, and were divided into observation group and control group according to the random number table method, 50 cases in each group. The control group were treated with enalapril maleate tablet, and the observation group were combinett with metoprolol on the basis of the control group. Clinical effect, cardiac function index, diastolic blood pressure, heart rate and cardiac function classification were observed in the two groups. Results：The total effective rate was 78.00% in the observation group, significantly higher than that of 58.00% in the control group （P〈 0.05 ）. After treatment, LVEDD, LADD and LVESD were significantly lower than those before treatment in the two groups （P〈0.05）, which of the observation group were significantly lower than those of the control group. LVEF was significantly higher than that before treatment （P〈0.05）, and that of the observation group was significantly higher than that of the control grol^p （P〈0.05）. Diastolic blood pressure, heart rate, systolic blood pressure in the two groups were significantly lower than those before treatment（P〈0.05 ）, and those of the observation group were significantly lower than those in the control group（P〈0.05）. Conclusion：Metoprolol can effectively improve patients＇ heart function and clinical effect in treatment of rheumatic heart disease complicated with chronic heart failure.