新发高血压与代谢性危险因素及生活方式的关系

Relationship between neo-hypertension and metabolic risk factors as well as lifestyle

目的探讨新发高血压与代谢性危险因素及生活方式的关系。方法采用分层整群随机抽样法,在2014年3-6月随机抽取唐山市4个社区内的11 072名居民作为调查对象,主要调查内容包括体格检测、血压测量、生化指标测定和生活方式调查。结果男性居民新发高血压发生率显著高于女性居民(χ~2=49.550,P<0.05);随着居民年龄增长,新发高血压发生率显著升高(χ~2=77.901,P<0.05);随着居民体质指数的升高,新发性高血压发生率显著升高(χ~2=566.801,P<0.05)。血压正常组居民总胆固醇含量低于新发性高血压组(t=9.048,P<0.05),两组居民空腹血糖、甘油三酯、LDL-C以及HDL-C水平差异无统计学意义(P>0.05)。吸烟、不吸烟以及戒烟居民中新发高血压发病率差异有统计学意义(χ~2=250.98,P<0.05);饮酒、不饮酒以及戒酒居民中新发高血压发病率差异有统计学意义(χ~2=499.95,P<0.05)。logistic多因素回归分析结果显示肥胖(OR=2.943,95%CI:1.765~4.910),饮酒(OR=3.353,95%CI:1.922~5.850),男性(OR=1.433,95%CI:1.133~1.813)和年龄增长(OR=1.600,95%CI:1.158~2.211)均为新发高血压的危险因素。结论新发高血压与代谢性危险因素包括肥胖、男性以及年龄增长,与饮酒也密切相关。

Objective To explore the relation between neo-hypertension and metabolic risk factors as well as lifestyle Methods A stratified cluster random sampling method was used to select 11,072 residents from 4 communities in Tangshan City from March to June, 2014 as the investigation objects. The main investigation items included physical examination, blood pressure measurement, biochemical index determination and life style survey. Results The incidence rate of neo-hypertension was significantly higher in male residents than in female ones （X^2= 49. 550, P〈0.05）. And it increased significantly with the increase of age （X^2 = 77.901, P〈0.05） and BMI （X^2 = 566. 801, P〈0.05）. The serum total cholesterol level was lower in the normal blood pressure group than in the neo-hypertension group （t= 9.048, P〈0.05）, but no statistically significant differences were found in the levels of fasting blood glucose, triglyceride, LDL-C and HDL-C between the two groups （P〉0.05）. The incidence rate of neo-hypertension showed statistically significant differences among smoking, non-smoking and smoking cessation residents （X^2= 250. 98, P〈0.05） as well as among drinking, non-drinking and drinking cessation residents （X^2= 499.95, P〈0.05）. Muhi-factor logistic regression a- nalysis showed that obesity （ OR = 2.943, 95%CI： 1.765-4.910）, drinking （ OR = 3.353,95%CI： 1.922-5. 850）, males （ OR = 1. 433, 95%CI： 1.133-1.813） and increase of age （ OR= 1.600, 95%CI： 1.158-2.211） were the risk factors of neo-hypertension. Conclusion Neo-hypertension is closely related to metabolic risk factors including obesity, males and increasing age, as well as to alcohol consumption.