新疆地区血友病患者HBV、HCV和HIV感染调查

A Survey of HBV,HCV and HIV Infections In Hemophilia Patients in Xinjiang Autonomous Region

目的了解新疆地区血友病患者乙型肝炎病毒(HBV)、丙型肝炎病毒(HCV)和人类免疫缺陷病毒(HIV)感染情况。方法对2008年5月~2014年6月新疆血友病诊疗中心确诊或治疗的210例血友病患者进行HBsAg、抗-HCV和抗-HIV检测,并根据年龄段进行分组。结果 210例血友病患者HBsAg、抗-HCV和抗-HIV阳性率分别为2.86%(6/210)、4.29%(9/210)和0.48%(1/210),总感染率为7.63%,不同年龄段患者HBsAg和抗-HCV阳性率的差异有统计学意义。结论新疆地区血友病患者HBV感染率低于一般人群,而HCV感染率高于一般人群,HIV感染有上升趋势,HBV和HCV感染与年龄密切相关。

Objective To understand the prevalence of hepatitis B virus （HBV） , hepatitis C virus （HCV） and human immunodeficiency virus （ HIV） of hemophilia patients in Xinjiang. Methods In 210 hemophilia patients admitted to our hospital from May 2008 to June 2014, serum HBsAg, anti-HCV and anti-HIV were measured. Results The positive rates of HBsAg, anti-HCV and anti-HIV in 210 hemophilia patients were 2.86% （6/210） , 4.29% （9/210）and 0.48% （1/210） , respectively.The overall infection rate was 7.63%. Positive rates of HBsAg and anti-HCV varied in ages of patients Conclusion The prevalence of HBV infection in hemophilia patients in Xinjiang area was lower than that in population of other places of China, and the prevalence of HCV infection in hemophilia patients was even higher. HIV infection tends to be increasing, and HBV and HCV infections in hemophilia patients were closely correlated with age of the pathients.