糖尿病患者认知功能评价及受损领域分析

The Cognition Impairment and Different Part for Cognitive Dysfunction of Diabetes Mellitus

目的:评估糖尿病患者认知功能受损的程度及受损的领域。方法:对194例糖尿病患者和156例健康对照者进行蒙特利尔认知功能评价量表(MoCA)及简易精神状态评价量表(MMSE)筛查。结果:整体认知功能评估结果显示,糖尿病组MMSE评分为(28.06±2.14)分,对照组的MMSE评分为(28.51±1.69)分,两组比较MMSE评分差异有统计学意义(P=0.033),糖尿病组MoCA评分为(27.24±1.81)分,对照组MoCA评分为(27.87±1.63)分;两组比较差异有统计学意义(P=0.001),其中MoCA的分项测试结果显示糖尿病组视空间与执行能力评分为(4.05±0.77)分,对照组为(4.29±0.62)分,两组比较差异有统计学意义(P=0.002);糖尿病组注意力评分(5.53±0.93)分,对照组为(5.73±0.44)分,两组比较差异有统计学意义(P=0.014);糖尿病组延迟回忆的评分(4.14±0.85)分,对照组为(4.39±0.57)分,两组比较差异有统计学意义(P=0.002)。结论:糖尿病患者认知功能明显低于健康人群。糖尿病患者认知功能障碍表现为多认知领域受损,以视空间与执行能力、注意力、延迟回忆为主。

Objective：To study the cognitive function and the different part for cognitive dysfunction in patients with diabetes.Method：Totally 194 patients with diabetes and 156 control subjects were selected.All cases were assessed by the Montreal cognitive assessment scale（MoCA）,Mini-Mental State Examination（MMSE）.Result：The scores of MMSE in the diabetes group and the contrl group were 28.06±2.14 and 28.51±1.69,the difference was significant（P=0.033）,MoCA in the diabetes group and the contrl group were（27.24±1.81） and（27.87±1.63）, the differences were significant（P=0.001）;MoCA in space and executive function,attention and delayed recall in the diabetes group were significant lower than those in the control group（4.05±0.77 vs 4.29±0.62;5.53±0.93 vs 5.73±0.44;4.14±0.85 vs 4.39±0.57）,the differences were significant（P=0.002,0.014,0.002）.Conclusion：The cognitive function of diabetes patients is significant lower than that of healthy people.The key points of cognition impairment in diabetes patients are space and executive function,attention,delayed recall.