多模式CT指导下急性脑梗死患者动脉溶栓与静脉溶栓的对比

Comparative Analysis of Arterial Thrombolysis and Intravenous Thrombolysis in Patients with Acute Cerebral Infarction Under Multi-mode

目的:探讨多模式CT指导下急性脑梗死患者动脉溶栓与静脉溶栓的疗效对比。方法:收集笔者所在医院颈动脉系统急性脑梗死患者85例,随机分为动脉溶栓组40例和静脉溶栓组45例,记录溶栓前、溶栓后2、24 h和7、30 d的NIHSS评分及生活能力状态。溶栓30 d后行疗效判定。结果:溶栓后,动脉溶栓组平均NIHSS评分结果均显著低于静脉溶栓组(P<0.05)。两组总显效率分别为65.00%和35.56%,动脉溶栓组优于静脉溶栓组(P<0.05)。结论:多模式CT指导的动脉溶栓与静脉溶栓是治疗急性脑梗死安全、有效的方法,且动脉溶栓临床疗效优于静脉溶栓。

Objective： To evaluate the safety and efficacy of multi-mode CT guided arterial thrombolysis and intravenous thrombolysis with rt-PA in treatment of acute cerebral infarction（ACI）.nethod： The carotid artery system in patients with acute cerebral infarction 85 cases were randomly divided into the arterial thrombolysis group of 40 patients and the intravenous thrombolysis of 45 patients, the NIHSS score and living ability status before thrombolysis and after thrombolysis 2 h, 24 h, 7 d and 30 d were recorded.The efficacy of thrombolysis after 30 days were determined.Result： After treatment, the average NIHSS score results in the arterial thrombolysis group were all significantly lower than the intravenous thrombolysis group（P〈0.05）.The total effective rate in two groups were 65.00% and 35.56% respectively, the arterial thrombolysis group was better than the intravenous thrombolysis group（P〈0.05）.Conclusion： Intra-arterial thrombolysis and venous thrombolysis guided by multi-mode CT are safe, effective in treatment of acute cerebral infarction, clinical efficacy of the former is superior to the latter.