七氟烷用于小儿诱导及维持麻醉的临床分析

Clinical Analysis of Sevoflurane in the Children Induction and Maintained Anesthesia

目的分析七氟烷用于小儿诱导及维持麻醉的临床效果,降低患儿手术疼痛感。方法方便选取2014年10月—2015年10月在该院接受择期手术的患儿46例,将所有患儿按照麻醉方式的不同,分为对照组23例、实验组23例;其中对照组患儿采用盐酸芬太尼以及丙泊酚静脉注射麻醉手段,实验组患儿采用七氟烷吸入麻醉手段,对比分析两组患儿术中心率和平均动脉压(MAP)、麻醉时间与苏醒时间、不良反应等情况。结果术后对照组患儿MAP指标为(81.9±8.8)mmHg、心率指标为(101.9±8.5)次/min、苏醒时间为(12.7±3.7)min、诱导时间为(4.9±0.4)min、拔管时间为(19.8±5.5)min;实验组患儿MAP指标为(72.5±7.9)mmHg、心率指标为(93.7±6.3)次/min、苏醒时间为(8.8±2.4)min、诱导时间为(1.6±0.5)min、拔管时间为(14.7±3.6)min。即实验组患儿麻醉指标优于对照组患儿;实验组患儿不良反应发生率为8.70%显著低于对照组患儿39.13%,两组患儿各数据之间差异有统计学意义(P<0.05)。结论在对患儿进行临床手术时,七氟烷麻醉药物的应用,具有诱导快、麻醉时间短、苏醒时间快以及不良反应发生率低的优势,可进行临床推广。

Objective To analyze the clinical effect of sevoflurane in the children induction and maintained anesthesia and reduce the operation pain of children.Methods 46 cases of children with selective operation in our hospital from October2014 to October 2015 were convenient selected and divided into two groups according to the anesthesia method with 23 cases in each,the control group adopted the intravenous injection anesthesia method of fentanyl and propofol,the experimental group adopted the inhalation anesthesia of sevoflurane,and the intraoperative heart rate,MAP,anesthesia time,awakening time and adverse reaction were compared between the two groups.Results The anesthesia indexes such as MAP,heart rate,awakening time,induction time,tube drawing time in the experimental group were better than those in the control group,[（81.9±8.8）mmHg,（101.9±8.5）times/min,（12.7±3.7）min,（4.9±0.4）min,（19.8±5.5）min vs（72.5±7.9）mmHg,（93.7±6.3）times/min,（8.8±2.4）min,（1.6±0.5）min,（14.7±3.6）min],and the incidence rate of adverse reactions in the experimental group was obviously lower than that in the control group（8.70% vs 39.13%）,and the difference had statistical significance（P〈0.05）.Conclusion The application of sevoflurane in clinical operation for children has the advantages of rapid induction,short anesthesia time,rapid awakening time and low incidence rate of adverse reactions.