氨氯地平联合缬沙坦治疗老年高血压合并糖尿病疗效观察

Observation on Curative Effect of Amlodipine Combined with Valsartan in Treatment of Senile Hypertension and Diabetes

目的探讨氨氯地平联合缬沙坦治疗老年高血压合并糖尿病的效果。方法选取该科2014年8月—2016年8月收治的高血压合并糖尿病老年患者120例,随机分为两组各60例,对照组采用缬沙坦治疗,观察组采用氨氯地平联合缬沙坦治疗。结果观察组总有效率为93.3%,明显优于对照组78.3%(P<0.05);治疗后观察组SBP、DBP、空腹血糖、餐后2 h血糖、糖化血红蛋白等下降程度明显优于对照组(P<0.05)。结论氨氯地平联合缬沙坦治疗老年高血压合并糖尿病疗效确切,值得应用。

Objective To discuss the effect of amlodipine combined with valsartan in treatment of senile hypertension and diabetes. Methods 120 cases of patients with senile hypertension and diabetes admitted and treated in our department from August 2014 to August 2016 were selected and randomly divided into two groups with 60 cases in each, the control were treated with valsartan, while the observation group were treated with amlodipine combined with valsartan. Results The total effective rate in the observation group was obviously better than that in the control group(93.3% vs 78.3%)(P<0.05), after treatment, the decrease degree of SBP, DBP FPG,2hPBG and HbA1c in the observation group was obviously better than that in the control group(P<0.05). Conclusion The curative effect of amlodipine combined with valsartan in treatment of senile hypertension and diabetes is definite, which is worth application.