女性生殖道解脲脲原体感染及其药敏分析

Ureaplasma urealyticum infection in female genital tract and drug sensitivity test

目的探讨女性生殖道解脲脲原体(Uu)的感染及其耐药性。方法选取2015年6月至10月于四川大学华西第二医院门诊进行常规妇科体检的719例受试者的宫颈管内分泌物标本为研究对象,受试者年龄为16~48岁。同时对Uu感染情况和耐药性进行分析。结果 (1)这719例进行常规妇科体检的受试者中,Uu检查结果呈阳性者为204例,阳性率为28.4%。其中25~35岁年龄段感染者为主(71.1%)。(2)药敏试验结果发现Uu对强力霉素、交沙霉素、四环素、普拉霉素等抗菌药物敏感,敏感度分别为97.1%、96.1%、95.6%、99.0%。但对氧氟沙星和环丙沙星的耐药性高,分别为76.5%和88.2%。结论根据药敏试验结果选择合适的抗菌药物对控制Uu感染、降低相关疾病发病率,以及保护育龄期妇女的健康具有重要意义。

ObjectiveTo analysis Ureaplasma urealyticum （Uu） infection in female genital tract and drug sensitivity test in order to provide a reference of using antibiotics.MethodsFrom June to October, 2015, a total of 719 patients with their cervical endocrine specimens, received routine gynecological examination were enrolled into this study. Subjects aged 16 to 48 years old. Then, the infection and drug sensitivity test of Uu were analyzed.Results①Among 719 cases, 204 cases were infected with Uu, accounting for 28.4%. And the infection women concentrated between 25 and 35 years old, accounting for 71.1%. ②The results of drug sensitivity test showed that the Uu was susceptible to doxycycline, josamycin, tetracycline, apramycin, and the sensitive rates were 97.1%, 96.1%, 95.6%, 99.0%, respectively. However, ofloxacin and ciprofloxacin had higher drug resistance rates, and the rates were 76.5% and 88.2%, respectively.ConclusionsBased on drug sensitivity test, appropriate antibiotics is beneficial to curbing the Uu infection and decreasing morbidity of relative diseases. It plays an important role in protecting the health of child-bearing age women.