热敏灸防治恶性肿瘤化疗所致虚证恶心呕吐的临床疗效观察

The Clinical Study of Thermal Moxibustion Preventing and Controlling Deficiency Syndrome of Nausea and Vomiting Caused by Malignant Tumor Chemotherapy

[目的]观察热敏灸联合昂丹司琼防治恶性肿瘤化疗所致的虚证恶心呕吐的效果,探索用热敏灸联合昂丹司琼的方法减轻化疗所致胃肠道不良反应的可行性,为进一步提高患者的生活质量,提供有效安全的治疗措施。[方法]将60例患者随机分为治疗组(30例)和对照组(30例),两组患者均行常规化疗方案,对照组采用昂丹司琼常规止呕,治疗组在对照组的基础上加用热敏灸灸治中脘、神阙、内关、足三里、胃俞穴,连续7天结束治疗,分别于第1天、第3天、第7天记录恶心呕吐及食欲症状积分。采用SPSS18.0软件系统,分析与评估治疗前后不同时间点的症状积分的变化。[结果]与对照组比较,治疗组恶心、呕吐、食欲各积分显著低于对照组,经检验,差异具有统计学意义(P<0.05,P<0.01)。[结论]热敏灸联合昂丹司琼能有效地降低恶性肿瘤化疗所致的虚证恶心呕吐的程度,可提高患者对化疗的耐受性。

[Objectives]Observation of thermal moxibustion combined Ondansetron prevention and treatment of the effect of deficiency syndrome nausea and vomiting by malignant tumor chemotherapy, to explore using thermal moxibustion combined Ondansetron method, it can reduce the feasibility of chemotherapy induced gastrointestinal adverse reaction, to further improve the life quality of patients, provide safe effective treatment measures.[Method]60patients were randomly divided into treatment group（30 cases） and control group（30 cases）, two groups of patients had comprehensive chemotherapy regimens, control group adopted Ondansetron conventional anti-nausea, on the basis of the control group, treatment group with thermal moxibustion used Zhongwan, Shenque（CV 8）, Neiguan（P6） Zusanli（ST36） and Weishu acupuncture points, and combined the Ondansetron treatment, the course of the treatment for 7 days, respectively, on day 1, day 3, 7, record nausea and vomiting and appetite symptoms integral. Using SPSS18.0 software system, analysis and evaluation of the symptoms of different time points before and after treatment the change of the integral. [Results]Compared with control group, treatment group of nausea, vomiting, loss of appetite each score significantly lower than the control group, the difference had statistical significance（ P0.05,P0.01））.[Conclusion]Thermal moxibustion combined with Ondansetron can effectively reduce the degree of deficiency syndrome nausea and vomiting caused by the malignant tumor chemotherapy, can effectively improve the patients＇ tolerance to chemotherapy.