2007-2015年广东省江门市人间布鲁氏菌病流行特征及职业人群血清学调查

Epidemiological and serological characteristics of human brucellosis in Jiangmen,Guangdong,2007-2015

目的了解广东省江门市布鲁氏菌病(布病)流行特征,为布病的防控工作提供参考依据。方法对江门市人间布病病例及布病监测点监测结果进行描述性分析。结果 2007-2015年江门市共报告人间布病病例121例,无死亡病例,年均发病率为0.30/10万,总体呈上升趋势(χ~2=136.94,P<0.001)。江门市累计病例最多的3个区(县)分别是新会区(46例)、蓬江区(21例)和鹤山市(18例),3个区(县)病例数占全市总病例数的70.25%;121例布病病例中,男性占66.12%,女性占33.89%;年龄以40~59岁人群为主,占总病例数的50.41%;最高发病的职业为农民,占总病例数的32.23%。2011-2015年报告的115例病例中,从发病-诊断间隔中位数为39 d;2012-2015年职业人群血清学累计监测825例,累计阳性率为0.73%。结论江门市人间布鲁氏菌病疫情上升趋势明显,需进一步落实监测任务,加强综合防治。

Objective To understand the epidemiological and serological characteristics of brucellosis in Jiangmen,Guangdong province,and provide scientific evidence for the prevention and control of brucellosis. Methods The descriptive epidemiological analysis was conducted by using the incidence data and surveillance results of human brucellosis in Jiangmen.Results From 2007 to 2015,a total of 121 brucellosis cases were reported with an average annual incidence of 0. 30/100 000,and no death case was reported. A significant increasing trend in brucellosis incidence during the period was observed（ χ2=136. 94,P〈0. 001）. The top 3 districts in reporting brucellosis cases were Xinhui（ 46 cases）,Pengjiang（ 21 cases） and Heshan（ 18 cases）,the cases reported in the 3 districts accounted for 70. 25% of the total. Of all the reported cases,66. 12%were males and 33. 89% were females,respectively; 32. 23% were owners of cattle and sheep and 50. 41% were aged 40-59 years. In the 115 reported cases from 2011 to 2015,the median interval between onset and diagnosis was 39 days. Totally 825 blood samples were collected from the owners of cattle and sheep from 2012 to 2015 and 6 were positive for Brucella antibody（ 0. 73%）. Conclusion The increasing trend of brucellosis incidence was obvious in Jiangmen. Further surveillance and comprehensive prevention and treatment should be conducted to control human brucellosis in Jiangmen.