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缺血后适应对女性心肌梗死患者急诊冠脉介入后微循环障碍的预防 被引量:7

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摘要 目的探讨缺血后适应对女性急性心肌梗死(STEMI)患者急诊冠状动脉介入术(PCI)中心肌微循环障碍的预防作用。方法就诊于医院诊断为首发心肌梗死的女性患者76例,随机分为缺血后适应(IPC)组和对照(CON)组,每组38例。所有患者均行PCI治疗,其中IPC组行缺血后适应术式。记录患者一般基线资料、术中资料、酶峰水平、心功能及随访不良事件。结果 IPC组三支冠脉的CTFC均高于CON组,IPC组术后TMPG 3级比例高于CON组,差异有统计学意义(P<0.05);IPC组无复流/缓血流发生率明显降低,差异无统计学意义(P>0.05)。IPC组心肌坏死标记物酶峰水平低于CON组,差异有统计学意义(P<0.05)。术后3 d左心室射血分数(LVEF)水平差异无统计学意义(P>0.05),院外1个月时IPC组LVEF水平高于CON组,2组患者各项不良事件IPC组发生率均低于CON组,但差异均无统计学意义(P>0.05)。结论缺血后适应可以预防接受急诊PCI的女性STEMI患者心肌微循环障碍、提高患者心功能水平。
出处 《河北医药》 CAS 2017年第9期1344-1347,共4页 Hebei Medical Journal
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