血清胆红素水平与冠状动脉SYNTAX评分的相关性研究

Correlation between serum bilirubin levels and coronary artery SYNTAX score

目的:探讨冠状动脉粥样硬化性心脏病(冠心病)患者血清胆红素水平与冠状动脉SYNTAX评分的相关性。方法:以2014-05~2015-08我院收治的69例冠心病患者为研究对象,根据患者冠状动脉SYNTAX评分分为低危组(27例)、中危组(23例)、高危组(19例)。采用ANOVA分析比较3组血清胆红素水平的差异,采用Spearman秩相关分析血清胆红素水平与SYNTAX评分的相关性。结果:低、中、高危3组患者血清总胆红素、间接胆红素水平差异有统计学意义(F=12.37,17.20,均P<0.01)。血清总胆红素、间接胆红素水平与冠状动脉SYNTAX评分呈显著负相关(r=-0.64,-0.73,均P<0.05)。结论:血清胆红素水平与冠状动脉病变程度呈负相关,可能与血清胆红素抗氧化作用有关。

Objective：To explore the correlation between serum bilirubin levels and coronary artery SYNTAX score of coronary heart disease.Methods：A total of 69 patients of coronary heart disease from May.2014 to Aug.2015 were selected,according to SYNTAX score,the patients were divided into the low risk group（27 cases）,medium risk group（23 cases）and high risk group（19 cases）.The diference of serum bilirubin concentrations among the three groups were compared by ANOVA,Spearman rank correlation analysis was used to analyze the correlation between serum bilirubin concentrations and coronary artery SYNTAX score.Results：ANOVA analysis showed the differences of serum total and indirect bilirubin concentrations among the groups were stafstitally signifcant（F=12.37,17.20,P0.01）.The Spearman correlation analysis showed that serum total and indirect bilirubin concentrations and coronary SYNTAX score were negatively corelated（r=-0.64,-0.73,P0.05）.Conclusion：Serum bilirubin levels and severity of coronary artery diseas were negatively correlated,which may be associated with serum bilirubin antioxidant properties.